The morphological data analysis of symptomatic abdominal aortic aneurysm and asymptomatic abdominal aortic aneurysm

Su Zhixiang, Guo Jianming, Guo Lianrui, Cui Shijun, Wu Yingfeng, Tong Zhu, Liu Yiren, Wei Lichun, Zhang Jian, Gu Yongquan

Journal of Abdominal Surgery ›› 2020, Vol. 33 ›› Issue (4) : 265-269.

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Journal of Abdominal Surgery ›› 2020, Vol. 33 ›› Issue (4) : 265-269. DOI: 10.3969/j.issn.1003-5591.2020.04.004

The morphological data analysis of symptomatic abdominal aortic aneurysm and asymptomatic abdominal aortic aneurysm

  • Su Zhixiang, Guo Jianming, Guo Lianrui, Cui Shijun, Wu Yingfeng, Tong Zhu, Liu Yiren, Wei Lichun, Zhang Jian, Gu Yongquan
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Abstract

Objective Abdominal aortic aneurysm(AAA) can be divided into symptomatic abdominal aortic aneurysm(sAAA) and asymptomatic abdominal aortic aneurysm (aAAA) according to its manifestations, and the purpose of this study was to investigate the difference and correlation of morphological data of the two groups.Methods January 2013 to January 2019 were included in the study. They were divided into symptomatic group (27 cases) and non-symptomatic group (80 cases) according to whether there was associated back and/or abdominal pain. According to the relevant data of computer tomography angiography (CTA), the differences and correlations of the main morphological indicators (maximum diameter of tumor, neck angle, etc.) between the two groups were analyzed and compared.Results The maximum diameter of the tumor in the sAAA group was greater than that in the aAAA group, with a statistically significant difference [(5.40±1.58) cm vs. (4.73±1.02) cm, P=0.047], for neck length [(2.87±1.27) cm vs. (2.76±1.43) cm, P=0.711] and neck angle (48.06°±36.06° vs. 36.66°±21.65°, P=0.131), with no statistically significant difference between the two groups, and the proportion of eccentric aneurysms was relatively higher in the sAAA group, with a statistically significant difference (51.9% vs. 30.0%, P=0.04). There was a negative correlation between neck length and the maximum diameter of the tumor (rs=-0.36, P<0.01), and a positive correlation between the angle of the neck and the maximum diameter of the tumor (rs=0.258, P=0.007).Conclusion In this study, there were statistically significant differences in the maximum diameter of the tumor, neck length, and geometric variables of neck angle between sAAA and aAAA, and the proportion of eccentric aneurysms was relatively higher in sAAA, which provided support for the aggressive clinical management of sAAA. There is a negative correlation between the length of the neck and the maximum diameter of the tumor, while there is a positive correlation between the angle of the neck and the maximum diameter of the tumor. The morphological variables of abdominal aortic aneurysm are also related to each other and interact with each other. However, the maximum diameter of the tumor alone cannot be used to predict the risk of abdominal aortic aneurysm rupture. It should also be analyzed from the perspective of hemodynamics and pathophysiology, which will make the prediction and determination more scientific.

Key words

Symptomatic abdominal aortic aneurysm / Non-symptomatic abdominal aortic aneurysm / Morphology

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Su Zhixiang, Guo Jianming, Guo Lianrui, Cui Shijun, Wu Yingfeng, Tong Zhu, Liu Yiren, Wei Lichun, Zhang Jian, Gu Yongquan. The morphological data analysis of symptomatic abdominal aortic aneurysm and asymptomatic abdominal aortic aneurysm[J]. Journal of Abdominal Surgery, 2020, 33(4): 265-269 https://doi.org/10.3969/j.issn.1003-5591.2020.04.004

References

[1] Sidloff D,Stather P,Dattani N.Aneurysm global epidemiology study:public health measures can further reduce abdominal aortic aneurysm mortality[J].J Vasc Surg, 2014,59(5):1471.DOI:10.1016/j.jvs.2014.03.266.
[2] Nevala T,Perälä J,Aho P,et al.Outcome of symptomatic,unruptured abdominal aortic aneurysms after endovascular repair with the Zenith stent-graft system[J].Scand Cardiovasc J, 2008,42(3):178-181.DOI:10.1080/14017430701819105.
[3] Harkin DW,Dillon M,Blair PH,et al.Endovascular ruptured abdominal aortic aneurysm repair (EVRAR):a systematic review[J].Eur J Vasc Endovascular Surg, 2007,34(6):673-681.DOI:10.1016/j.ejvs.2007.06.004.
[4] Chandra V,Trang K,Virgin-Downey W,et al.Long-term outcomes after repair of symptomatic abdominal aortic aneurysms[J].J Vasc Surg, 2018,68(5):1360-1366.DOI:10.1016/j.jvs.2018.02.036.
[5] Chaikof EL,Dalman RL,Eskandari MK,et al.The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm[J].J Vasc Surg, 2018,67(1):2-77.e2.DOI:10.1016/j.jvs.2017.10.044.
[6] Moll FL,Powell JT,Fraedrich G,et al.Management of abdominal aortic aneurysms clinical practice guidelines of the European society for vascular surgery[J].Eur J Vasc Endovascular Surg, 2011,41:S1-S58.DOI:10.1016/j.ejvs.2010.09.011.
[7] Nicholls SC,Gardner JB,Meissner MH,et al.Rupture in small abdominal aortic aneurysms[J].J Vasc Surg, 1998,28(5):884-888.DOI:10.1016/s0741-5214(98)70065-5.
[8] Greenhalgh RM,Forbes JF,Fowkes FG. Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms[J].Lancet, 1998,352(9141):1649-1655.DOI:10.1016/s0140-6736(98)10137-x.
[9] Malkawi AH,Hinchliffe RJ,Xu Y,et al.Patient-specific biomechanical profiling in abdominal aortic aneurysm development and rupture[J].J Vasc Surg, 2010,52(2):480-488.DOI:10.1016/j.jvs.2010.01.029.
[10] Khosla S,Morris DR,Moxon JV.Meta-analysis of peak wall stress in ruptured,symptomatic,and intact abdominal aortic aneurysms[J].J Vasc Surg, 2015,61(3):836-837.DOI:10.1016/j.jvs.2015.01.021.
[11] Soto B,Vila L,Dilmé J,et al.Finite element analysis in symptomatic and asymptomatic abdominal aortic aneurysms for aortic disease risk stratification[J].Int Angiol, 2018,37(6):479-485. DOI:10.23736/s0392-9590.18.03994-9.
[12] Soto B,Vila L,Dilmé JF,et al.Increased peak wall stress,but not maximum diameter,is associated with symptomatic abdominal aortic aneurysm[J].Eur J Vasc Endovascular Surg, 2017,54(6):706-711.DOI:10.1016/j.ejvs.2017.09.010.
[13] Chisci E,Kristmundsson T,de Donato G,et al.The AAA with a challenging neck:outcome of open versus endovascular repair with standard and fenestrated stent-grafts[J].J Endovascular Ther, 2009,16(2):137-146.DOI:10.1583/08-2531.1.
[14] Koncar IB,Nikolic D,Milosevic Z,et al.Morphological and biomechanical features in abdominal aortic aneurysm with long and short neck:case-control study in 64 abdominal aortic aneurysms[J].Ann Vasc Surg, 2017,45:223-230.DOI:10.1016/j.avsg.2017.06.054.
[15] Stenbaek J,Kalin B,Swedenborg J.Growth of thrombus may be a better predictor of rupture than diameter in patients with abdominal aortic aneurysms[J].Eur J Vasc Endovascular Surg, 2000,20(5):466-469.DOI:10.1053/ejvs.2000.1217.
[16] 蔡彦,许世雄,景在平,等.腹主动脉瘤几何形态对血液动力学影响的三维数值分析[J].医用生物力学,2008,23(2):140-146.
[17] 张强,罗英伟,王新文,等.腹主动脉瘤形态学特点及临床意义[J].中华外科杂志,2001,39(8):583-585.
[18] 叶红,李宇,俞婧,等.大、小肾下型腹主动脉瘤的CT形态学特点[J].中国介入影像与治疗学,2010,7(1):38-42.
[19] Rengarajan B,Wu W,Wiedner C,et al.A comparative classification analysis of abdominal aortic aneurysms by machine learning algorithms[J].Ann Biomed Eng, 2020,48(4):1419-1429.DOI:10.1007/s10439-020-02461-9.
[20] 王胜煌,吴彩云.炎症反应与氧化应激在腹主动脉瘤发病机制中的新观点[J].中华内科杂志,2013,52(9):787-788.
[21] Courtois A,Nusgens BV,Hustinx R,et al.18F-FDG uptake assessed by PET/CT in abdominal aortic aneurysms is associated with cellular and molecular alterations prefacing wall deterioration and rupture[J].J Nucl Med, 2013,54(10):1740-1747.DOI:10.2967/jnumed.112.115873.
[22] Georgakarakos E,Ioannou C,Kostas T,et al.Inflammatory response to aortic aneurysm intraluminal thrombus may cause increased 18F-FDG uptake at sites not associated with high wall stress:comment on "high levels of 18F-FDG uptake in aortic aneurysm wall are associated with high wall stress"[J].Eur J Vasc Endovascular Surg,2010,39(6):795.DOI:10.1016/j.ejvs.2010.02.020.
[23] Conlisk N,Forsythe RO,Hollis L,et al.Exploring the biological and mechanical properties of abdominal aortic aneurysms using USPIO MRI and peak tissue stress:a combined clinical and finite element study[J].J Cardiovasc Trans Res, 2017,10(5/6):489-498.DOI:10.1007/s12265-017-9766-9.
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